Natural Sources of Inhibition of Adenosine Diphosphate-Induced Platelet Aggregation

Authors

  • Marwa A.A. Fayed Department of Pharmacognosy, Faculty of Pharmacy, University of Sadat City, Sadat City 32897, Egypt
  • Waheed Ul Islam Hira Pharmacy, Dubai, United Arab Emirates
  • Muhammad Hanif Bangash Pakistan Institute of Nuclear Science and Technology Islamabad, Pakistan

DOI:

https://doi.org/10.55627/ppc.001.01.0102

Keywords:

Platelet Aggregation, adenosine diphosphate, medicinal plants, cardiovascular diseases

Abstract

Platelets are central in mediating cardiovascular diseases including thrombosis. Aggregation of platelets is an important process following the adhesion of platelets to the injury site which may lead to the formation of a thrombus. Various aspects of platelet activation and aggregation could be modulated with compounds or fractions isolated from natural sources. This review summarizes these natural sources of inhibition against one of the most relevant physiological and pathological platelet agonists-adenosine diphosphate. Reported literature on the subject is further explored to discuss phytocompounds isolated from crude extracts or polarity-based fractions. Structures of the active compounds and their structure-activity relationship are also discussed.

 

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Published

2021-12-29

How to Cite

Natural Sources of Inhibition of Adenosine Diphosphate-Induced Platelet Aggregation. (2021). Phytopharmacological Communications , 1(1), 49=63. https://doi.org/10.55627/ppc.001.01.0102

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