Discovery of Anti-inflammatory Compounds from Pleione Grandiflora.
DOI:
https://doi.org/10.55627/ppc.001.01.0060Abstract
An investigation of the pseudobulbs of Pleione grandiflora (Rolfe) yielded several new glucosyloxybenzyl 2-hydroxy-2-isobutylsuccinates, pleionesides. Acidic and Alkaline hydrolysis experiments alongside analytical techniques namely NMR and HRESIMS were used to determine the structure and configuration of these novel phytocompounds. These compounds were subjected to LPS-induced BV2 microglia for potential anti-inflammatory effect. Results showed that 3 of these compounds possess moderate activity compared with quercetin used as a positive control. Fitoterapia. 2021 Nov;155:105062.
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2021-12-30
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Discovery of Anti-inflammatory Compounds from Pleione Grandiflora. (2021). Phytopharmacological Communications , 1(1), 05-07. https://doi.org/10.55627/ppc.001.01.0060
