Wound Healing by Italian and Algerian Resins

Abstract

One of the most common traditional medicine remedies used for wound healing is the oleoresin preparation of Pistacia vera. However, no scientific rationale has been provided for the wound healing properties of the plant and its resins. Boudjelal and associates using a circular wound healing model assessed the ability of the plant collected from Algeria and Italy for in-vivo wound healing. Their results exhibited a high terpenoid content in the plant and significant healing effects. From day 8 to day 16 significant wound contraction was seen upon application of Algerian and Italian oleoresin ointment preparation. The results were comparable to the standard drug used, Cicatryl. Histological tissue results corroborated the in vivo results. The lack of toxicity was confirmed by applying the ointments to the skins of rabbits. The authors argue that their investigation supports the traditional practice of using Pistacia vera as an effective remedy for healing wounds and injuries. Fitoterapia. 2022 Jun;159:105197.